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The 2023 ÃÛÑ¿´«Ã½ is the largest public funder of biomedical research in the world. The NIH invests most of its nearly $48 billion budget in medical research seeking to enhance life and to reduce illness and disability. NIH-funded research has led to breakthroughs and new treatments helping people live longer, healthier lives, and building the research foundation that drives discovery.